Make an Educated Decision: Sounds Science Supports SBOs for Daily Use

22 Proven Benefits of Soil-Based Probiotics

The ancient and beneficial soil-born organisms (SBOs) in PrescriptBiotics™ have 37 years of research to back them, with remarkable results detailed in over 700 pages of clinical trials and studies. The friendly, naturally-derived SBOs in PrescriptBiotics™ have at least 22 research-backed benefits, with many more positive health effects reported by long-term users.*

The daily benefits of using PrescriptBiotics™ Bio-Identical SBOs are supported by 22 explicit and implicit claims. These SBOs: [9, 11]

  1. Break down unnecessary and dangerous waste materials and prevent their buildup in the colon.
  2. Bond to and flush toxic heavy metals from the body.
  3. Bring gut microbes and gut health back into balance.
  4. Bring immunity and colonic pH back into balance.
  5. Change and often improve metabolism.
  6. Communicate within the body’s intricate signaling network, directing it to perform necessary tasks and regulate bodily functions that may have grown sluggish.
  7. Encourage Lactoferrin production, needed to modulate the immune system and defend the body against harmful bacteria and infection.
  8. Help to maintain healthy immune function in children and adults.
  9. Improve intestinal nutrient absorption.
  10. Keep pathogenic bacteria and fungi from taking up residence in the gut.
  11. Minimize and often eliminate bloating and gas.
  12. Regulate and improve bowel elimination.
  13. Restore healthy levels of good gut bacteria that are missing.
  14. Produce building blocks used by the body to activate its natural digestive enzymes.
  15. Produce protective compounds that replenish malnourished or wounded cells.
  16. Provide safe microbial stimulation for developing infants.
  17. Provide a safe source of healthy gut bacteria for developing children.
  18. Stop free-radical-producing enzymes from forming.
  19. Strengthen overall immunity.
  20. Support daily health and lifelong well-being.
  21. Support the production of natural antibodies to make the immune system even stronger.
  22. Work as a powerful and protective antioxidant in the body.


Science Says Soil-Based: Summaries of SBO Research

Ancient gut diversity.

A healthy gut requires large amounts of good bacteria — the more diverse, the better. Today’s guts are far different from what our ancestors’ guts once were, at a time when friendly soil-based bacteria were plentiful, and good bugs arrived in the gut straight from the earth. In most modern guts (those that haven’t been replenished with SBO bacteria), these multitudes of hardy, diverse bacteria have been virtually eliminated. Soil-born organisms are the same “good bugs” our ancestors ate from farm-to-table, gleaned daily from unwashed fruits and vegetables. These SBOs are the good bacteria missing from today’s processed food diets. (National Institutes of Health, 2012 June 13; Cell Reports, 2015; Journal of Physiological Anthropology, 2015.)

Behavior, mood, and chronic disease.

Replacing any missing SBO bacteria in the gut is critical, or else our health suffers. Research has provided a direct link between our gut health and our behavior, mood, immunity, and risk for chronic disease — including cancer and diabetes. In 2012, a University of Medicine and Dentistry of New Jersey-School of Health Related Professions team discovered that taking a probiotic supplement could strengthen immunity enough to reduce the duration and severity of the common cold and upper-respiratory-tract infections among college students. A 2014 study published in the Journal of Physiological Anthropology explored the “ancient art” of fermented foods and drinks and how probiotics positively influence mood, confirming that high-fat, high-sugar modern convenience foods are “at odds with our evolutionary past… not only undermining optimal nutritional status, [but] have untold effects on the microbiome and ultimately the brain.” In 2016, Iranian researchers learned that probiotics can improve cognitive function in Alzheimer’s patients; the same year, a University of California Los Angeles study provided evidence that anti-inflammatory, beneficial gut bacteria could stop or slow the progression of some cancers. And in 2017, Finnish researchers found that gut bacteria can protect against type 2 diabetes by producing a protective metabolite called indolepropionic acid to regulate insulin. (Frontiers in Aging Neuroscience, 2016; Journal of Physiological Anthropology, 2014; British Journal of Nutrition, 2012; PLOS ONE, 2016; Scientific Reports, 2017.)

Communication and immunity.

It’s become common knowledge in the past decade that probiotics can improve gut and whole-body health at myriad levels. As scientific breakthroughs emerged, scientists began to narrow their scope to explore SBOs’ profound effect on the gut. Most notably, soil-based probiotics have been lauded for their ability to communicate. SBOs communicate with the immune system and the entire body through the epithelial cells in the gut lining; SBOs provide direction using a complex chemical messenger system, as Heyman and Husebye explained in their published research. The gut has also been called the “second brain” because of its ability to communicate with and direct the body. (Heyman, et al., 2002 and Husebye et al., 2001; Journal of Medicinal Food. 2014.)

Digestion and elimination.

Supplying the gut with the beneficial soil-based organisms it’s missing can help to restore the balance of “good versus bad” gut bacteria. Once SBOs replenish the gut so that bad bacteria no longer overpower the good, health benefits are likely to follow. Some of the most common SBO benefits include enhanced nutrient absorption and bolstered immunity (as cited above), as well as improved digestion and elimination. Microbiologist Professor Lee Dexter, who dedicated her life’s work to cataloging and identifying more than 600 SBO species when working with the USDA, reported in her published research that SBO bacteria have a particular advantage. Spore probiotics are a specialized type of bacteria found in soil, Professor Dexter explained. When spore probiotics, such as bacillus, encounter non-spore-forming probiotics, such as lactobacillus, they create a group called “consortia.” Soil-born bacteria consortia found in nature, living as microorganism communities, have a distinct symbiosis where each microbe benefits from the other microbes’ activity. So, naturally-occurring SBO consortia work harmoniously together, even forming their own encapsulating matrix for protection and strength, to create balance in the human gut just as they do in nature. (Professor Lee B. Dexter, March 2010.)

Protection and nourishment.

With 37 years of research to back its use by people and pets, PrescriptBiotics™ is a well-studied SBO probiotic. Worldwide marketing rights were secured for the unique PrescriptBiotics™ SBO formulation in 1995, and for the past two decades and counting, manufacturers have remained steadfast in their commitment to providing the most effective and the safest naturally-friendly family probiotic. When used regularly, PrescriptBiotics™ SBOs help break down waste and toxins into smaller molecules that are easy to pass through the digestive system and prevent new waste formation; produce antimicrobial compounds that can keep harmful organisms from puncturing or adhering to the gut wall; function as a protective antioxidant to scavenge the free radicals known to cause disease, as well as prevent the enzymes that create free radicals from forming in the first place; and produce more antioxidants and vitamins that are needed to nourish the body, especially the liver and the colon. (Executive Summary, Body Biotics.)

Proof Is in the Probiotic: Testimonials from Satisfied Users

Been using this for years!

“This is a great product! My family has been using this for years now! This absolutely will improve your gut flora!” – Rhonda

Five stars.

“Best product on the market today.” – Michael

It works great on dogs.

“I sprinkle a little in my dog’s food every night. No dog dewormer need here. No sickness for him. Don’t have to worry about him eating stuff out back and getting sick. It works and is holistic. IT REALLY WORKS!” – Meg

Great probiotic supplement!

“Really good probiotic product. Big help in my battle with Candida… A blessing.” – Harley

Great product! I love these biotics.

“Great product! I love these biotics! For some reason, I have purchased other biotics that upset my stomach! But, this brand does NOT!
Will order again.” – Valerie

The best.

“Foundation of my health. I would not be without it. I recommend it to anyone interested in maintaining a healthy immune system and warding off colon cancer.” – Olivia


*Note: Customer statements have not been evaluated by the Food and Drug Administration. 

  1. NIH News & Events [Internet]. Bethesda, Maryland: National Institutes of Health. NIH Human Microbiome Project defines normal bacterial makeup of the body; 2012 June 13.
  2. Inés Martínez, James C. Stegen, Maria X. Maldonado-Gómez, A. Murat Eren, Peter M. Siba, Andrew R. Greenhill, Jens Walter. The Gut Microbiota of Rural Papua New Guineans: Composition, Diversity Patterns, and Ecological Processes. Cell Reports, 2015; DOI: 10.1016/j. celrep.2015.03.049.
  3. Logan AC, Katzman MA, Balanzá-Martínez V. Natural environments, ancestral diets, and microbial ecology: is there a modern “paleo-deficit disorder”? Part II. Journal of Physiological Anthropology. 2015;34(1):9. doi:10.1186/s40101-014-0040-4.
  4. Elmira Akbari, Zatollah Asemi, Reza Daneshvar Kakhaki, Fereshteh Bahmani, Ebrahim Kouchaki, Omid Reza Tamtaji, Gholam Ali Hamidi, Mahmoud Salami. Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer’s Disease: A Randomized, Double-Blind and Controlled Trial. Frontiers in Aging Neuroscience, 2016; 8 DOI: 10.3389/fnagi.2016.00256.
  5. Selhub EM, Logan AC, Bested AC. Fermented foods, microbiota, and mental health: ancient practice meets nutritional psychiatry. Journal of Physiological Anthropology. 2014;33(1):2. doi:10.1186/1880-6805-33-2.
  6. Tracey J. Smith, Diane Rigassio-Radler, Robert Denmark, Timothy Haley, Riva Touger-Decker. Effect of Lactobacillus rhamnosus LGG® and Bifidobacterium animalis ssp. lactis BB-12® on health-related quality of life in college students affected by upper respiratory infections. British Journal of Nutrition, 2012; 1 DOI: 10.1017/S0007114512004138.
  7. Amrita K. Cheema, Irene Maier, Tyrone Dowdy, Yiwen Wang, Rajbir Singh, Paul M. Ruegger, James Borneman, Albert J. Fornace Jr, Robert H. Schiestl. Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis. PLOS ONE, 2016 DOI: 10.1371/journal.pone.0151190.
  8. Vanessa D. de Mello, Jussi Paananen, Jaana Lindström, Maria A. Lankinen, Lin Shi, Johanna Kuusisto, Jussi Pihlajamäki, Seppo Auriola, Marko Lehtonen, Olov Rolandsson, Ingvar A. Bergdahl, Elise Nordin, Pirjo Ilanne-Parikka, Sirkka Keinänen-Kiukaanniemi, Rikard Landberg, Johan G. Eriksson, Jaakko Tuomilehto, Kati Hanhineva, Matti Uusitupa. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Scientific Reports, 2017; 7: 46337 DOI: 10.1038/srep46337.
  9. Heyman, et al., 2002 and Husebye et al., 2001 pdf ; [Rolfe, 2002], [Lin, et al., 1999], [Bravo, 1998, Tieking, et al., 2003, Zvauya, et al., 1997, Seppo,et al., 2003, Calderon, et al., 2003, Mensah, et al., 1995, and Olsen, et al., 1995].
  10. Galland L. The Gut Microbiome and the Brain. Journal of Medicinal Food. 2014;17(12):1261- 1272. doi:10.1089/jmf.2014.7000.
  11. Structure/Function Claims for Soil-Based Organisms™, Manufactured by Life Science Products, Inc., Houston, Texas. Executive Summary, Body Biotics.
  12. Professor Lee B. Dexter, March 2010. The Safety and Efficacy of Bacillus sp. as Probiotics, Body Biotics.